Never Sick Part 2

****The 4mg of Melatonin in here are amazing for sleep, healing, auto-immune disorders, growth hormone, cancer......did I also mention you will sleep really really well with it :)

 

The following is an excerpt on ImmuPro (From Gary Young) and following the excerpt is scientific studies I found (Connie Bynum compiled).

 

"…ImmuPro…Our next product..one that I am really excited about, because again, it is a product we have used at the Clinic and with which we have seen phenomenal results.  We have tremendous research documenting the effects of this product, and now it will be yours.  This product is primarily made up of lycium polysaccharide.  It is the primary element in the wolfberry that has been found to augment and enhance the immune system, decrease tumor cell growth, and help in the promotion of longevity.  It is one of the most important immune stimulating discoveries that has been made in the last decade–even in the last two decades.   Research at the Department of Microbiology tested wolfberry polysaccharide and immune therapy on 79 advanced cancer patients.  Treatment using the polysaccharide markedly increased in natural killer cells.  In addition, polysaccharide more than doubled the effectiveness of interleukin-2 immune therapy.

 

It is important for you to know that when they are using natural ingredients they always try to couple it with another compound.  This was very interesting to me because I also have found that when I compound ingredients that is when we find the greatest results, and we have definitely seen and proven that over the years with our blends of oils.

 

Medical college researchers concluded that lycium polysaccharides were highly effective in promoting immunity.  The lycium fruit was effective in avoiding the decrease in the number of white cells.  We have watched this with our patients at the Clinic and we have taken another step further again.  Mark is the one who pushed this forward and brought it to completion for us.

 

Agarius, one of the most powerful stimulants yet to be discovered, is a medicinal mushroom from Brazil that contains a rich complex of betaglukins, a type of polysaccharide which stimulates both humoral B-cells and cell media T-cells immunity.

 

University studies in Japan identify betaglukin polysaccharides that raised levels of immune cells. Populations of pan T-cells jumped 43%, helper T-cells 37% and killer T-cells 50% following oral administration of this polysaccharide. 

 

Folks, is this interesting to you?  I shared with you earlier and told you that this year was about documentation and the proof of the products that we are putting into your hands, so that when you go out there with it, this is not folklore medicine and you are not going to be talking about it as such. 

You are going to talk about it with the backup of hard copy, university documented research.

 

The Marvelous Maitake

The Maitake mushroom, according to Raymond Chang, MD of the Memorial Sloan-Kettering Cancer Center,

has various degrees of immune modulating, lipid-lowering anti-tumoral and other beneficial health effects without any significant toxicity. A 2001 study conducted at the Toya Medical and Pharmaceutical University in Japan found that Maitake  polysaccharides drastically increased the killing power of macrophage immune cells. 

 

A recent study by researchers at the New York Medical College, found that polysaccharides from Maitake drastically slowed the growth of prostate tumor cells.  Even more surprising, it was determined that vitamin C enhanced the effect of polysaccharides by 8 to 16 times. Again, what did that just say..that vitamin C enhanced the effect?  And what is in wolf-berry, and how many times higher is it than natural ascorbic acid?  Do you see what happens here when we start compounding these formula?

 

Extraordinary Polysaccharides

 

We have research at the Veterans' General Hospital in Taiwan showed that the gamaderma polysaccharides stimulated human immune cells, macrophages and T-lymphacytes, too, dramatically increase their output of Interleukin-1, Interleukin-6, T and F and gamma interferon.

 

Recent studies at the Chinese Academy of Sciences in Shanghai found that Reishi polysaccharides multiplied T-cells by over 50%, B-cells by 55%, immuglobulan-G by almost 10%.  Further studies identified 1.3 beta glucans, 1.4 beta glucans, and 1.6 beta glucans which dramatically enhance counts of T- and B-lymphocytes involved in both cell mediated and humoral immunity.  Larch polysaccharides derived from the larch accidentalists larch tree grows in St. Maries.  The tree uses the polysaccharides to heal itself after lightning strikes.  Larch polysaccharides occur naturally in other immune stimulating herbs.

Research of an institute in Germany has shown that the polysaccharides activate NK (natural killer) cells by increasing levels of gamma interferon.

 

More About ImmuPro

 

Zinc.  The experimental depletion of zinc has been shown to produce a number of deficiencies, including impairment of antibody response, decreased numbers of T- and B-lymphocytes, loss of cyrotoxic T-lymphocyte response and finding embolution in T-cell depletion in spleen and lymph nodes.

Every ingredient in your ImmuPro is documented for its effectiveness..not just one or two, but every single ingredient.  Cancer patients who were mightily deficient in zinc were also found to have markedly lower Interleukin through gamma interferon and natural killer cell levels. 

 

John Hopkins research recently examined the effect of zinc on 1154 low birth weight infants and found that daily doses of 5 mg. of zinc reduced mortality from infectious disease by over 68% compared with non-supplemented children.

 

Selenium..multiplies Interleukin-2 receptors according to the New York University research.  This is where the oils play such an integral part of your formulations because when people have a disease  (regardless of what it is) the receptor sites are greatly compromised, and when they are compromised they can't pick up those nutrients and ingredients that are important for them to create the replicating of healthy cells, so you can be eating good things and taking good things into your body, but if the body can't receive it and utilize it, naturally it doesn't have much value.

 

ImmuPro is Chewable!

 

 

Powerful Limonene

 

It was interesting that after September 11 last year we sold out of Thyme in just a matter of three or four days.  There was a big rush on it.  Clove, the strongest antioxidant, is highest on the ORAC of the Essential Oils.  Orange, rich in limonene. 

 

There is tremendous research coming out now on Orange and Grapefruit oil, and naturally Lemon oil on the value of limonene as an anti-tumoral agent and even some case studies.  This was a case study that was conducted several years ago at the Wisconsin University.  Dr. Michael Ghoul's colleagues found that 5% limonene (a diet fed to test animals for 18 to 30 weeks) resulted in a 66% drop in mammary tumor incidence and a 42% drop in animals with a palatable tumor. 

 

I received this research a number of years ago and I got really excited and called and tried to talk to the department about it, but it was sad that the research was being conducted on a synthetic limonene to see what the results were.  When they saw the results were so effective they went on to do studies with natural limonene extracted from Orange peel oil. It was very exciting!  You see here again the effects of Orange oil and the limonene on tumor incidents.  Of course, the cortisol levels shoot and the antioxidant activity and the limonene, how it brings that down, so it is really a powerful anti-tumoral agent.

 

In 1997 in the Department of Medical Oncology at the Taurene Cross Hospital in London 32 patients with advanced breast and colon cancer completed 99 courses of limonene administrated orally.  Dosages ranged from 1 gram to 16 grams per day and researchers found promising results…."

 

ImmuPro contains some of the following:

 

Ningxia wolfberry polysaccharide (Lycium barbarum)

• lycium polysaccharide…is the primary element in the wolfberry that has been found to augment and enhance the immune system, decrease tumor cell growth, and help in the promotion of longevity.  It is one of the most important immune stimulating discoveries that has been made in the last decade–even in the last two decades.  
•  Research at the Department of Microbiology tested wolfberry polysaccharide and immune therapy on 79 advanced cancer patients.  Treatment using the polysaccharide markedly increased in natural killer cells.  In addition, polysaccharide more than doubled the effectiveness of interleukin-2 immune therapy.
• The following were found on www.Pubmed.com
  • Lycium barbarum polysaccharides induce apoptosis in human prostate cancer cells and inhibits prostate cancer growth in a xenograft mouse model of human prostate cancer. Luo Q, Li Z, Yan J, Zhu F, Xu RJ, Cai YZ.  College of Public Health, Wuhan University, Wuhan, Hubei, China.
  • Growth inhibition and cell-cycle arrest of human gastric cancer cells by Lycium barbarum polysaccharide. Miao Y, Xiao B, Jiang Z, Guo Y, Mao F, Zhao J, Huang X, Guo JMed Oncol. 2009 Aug 11.
  • Lycium barbarum inhibits growth of estrogen receptor positive human breast cancer cells by favorably altering estradiol metabolism. Life Sci. 2005 Mar 18;76(18):2115-24.
  • Effect of lycium barbarum polysaccharide on human hepatoma QGY7703 cells: inhibition of proliferation and induction of apoptosis  Zhang M, Chen H, Huang J, Li Z, Zhu C, Zhang S. Department of Food Science and Bioengineering, Tianjin University of Science and Technology, Tianjin 300222, PR China. zm0102@sina.com
  • Lycium barbarum polysaccharide (LBP), extracted from Lycium barbarum that is a kind of traditional Chinese herb, is found to have anticancer activity. In this study, the effect of LBP on the proliferation rate, cell cycle distribution and apoptosis in the human hepatoma QGY7703 cell line were investigated. The effects of this compound were also tested on the concentration of calcium in cells. LBP treatment caused inhibition of QGY7703 cell growth with cycle arrest in S phase and apoptosis induction. The amount of RNA in cells and the concentration of intracellular Ca2+ were increased. Moreover, the distribution of calcium in cells was changed. Taken together, the study suggests that the induction of cell cycle arrest and the increase of intracellular calcium in apoptotic system may participate in the antiproliferative activity of LBP in QGY7703 cells.

 Reishi mycelia (Ganoderma lucidum)

• Ganoderma lucidum extract induces cell cycle arrest and apoptosis in MCF-7 human breast cancer cell.  International Journal of Cancer, Volume 102 Issue 3, Pages 250-253.
• Gao Y, et al. Effects of Ganopoly ( Ganoderma lucidum Polysaccharide Extract) on the Immune Functions in Advanced-Stage Cancer Patients. Immunol Invest 2003;32(3): 201-15. Thirty-four patients with advanced-stage cancer of various tissues were given 1800 mg of oral Ganopoly three times daily before meals for 12 weeks. Cytokines, T-cell subsets, and natural killer activity were measured to assess the effects of Ganopoly. Researchers found a significant increase in T-cell populations and NK activity at the 12-week period compared to baseline although the mechanism is unclear. More studies are needed to confirm these observations.
• 
  
•  From Wikipedia:
  • May possess anti-tumor, immunomodulatory and immunotherapeutic activities, supported by studies on polysaccharides, terpenes, and other bioactive compounds isolated from fruiting bodies and mycelia of this fungus (reviewed by R. R. Paterson and Lindequist et al.).
  • It has also been found to inhibit platelet aggregation, and to lower blood pressure (via inhibition of angiotensin-converting enzyme), cholesterol and blood sugar.
  • Laboratory studies have shown anti-neoplastic effects of fungal extracts or isolated compounds against some types of cancer. In an animal model, Ganoderma has been reported to prevent cancer metastasis, with potency comparable to Lentinan from Shiitake mushrooms.
  • The mechanisms by which G. lucidum may affect cancer are unknown and they may target different stages of cancer development: inhibition of angiogenesis (formation of new, tumor-induced blood vessels, created to supply nutrients to the tumor) mediated by cytokines, cytoxicity, inhibiting migration of the cancer cells and metastasis, and inducing and enhancing apoptosis of tumor cells.
  • Additional studies indicate that ganoderic acid has some protective effects against liver injury by viruses and other toxic agents in mice, suggesting a potential benefit of this compound in the treatment of liver diseases in humans, and Ganderma-produced sterols inhibit lanosterol 14α-demethylase activity in the biosynthesis of cholesterol.
  • Ganderma compounds inhibit 5-alpha reductase activity in the biosynthesis of dihydrotestosterone
  • Besides effects on mammalian physiology, Ganoderma is reported to have anti-bacterial and anti-viral activities. Ganoderma is reported to exhibit direct anti-viral with the following viruses; HSV-1, HSV-2, influenza virus, vesicular stomatitis.
  • Ganoderma mushrooms are reported to exhibit direct anti-microbial properties with the following organisms; aspergillus niger, bacillus cereus, candida albicans, and escherichia coli.

Maitake mycelia (Grifola frondosa)

•  The Maitake  mushroom, according to Raymond Chang, MD of the Memorial Sloan-Kettering Cancer Center, has various degrees of immune modulating, lipid-lowering anti-tumoral and other beneficial health effects without any significant toxicity.
• Clinical Summary from Memorial Sloan-Kettering Cancer Center
  • The active constituent is thought to be a beta-glucan polysaccharide. The whole mushroom is used primarily as a dietary element, but extracts and supplements are sold as immune stimulants for patients with HIV or cancer. While no adverse effects have been reported, some studies reveal a hypoglycemic effect following administration of maitake extract.
  • Maitake was shown to enhance bone marrow colony formation, reduce doxorubicin toxicity in vitro, and to inhibit tumor metastasis.
  • In a small non-controlled study, tumor regression or significant symptom improvements were observed in half of the subjects using Maitake extract.
  • In another study of postmenopausal breast cancer patients, oral administration of maitake extract was shown to have immunostimulatory as well as immune inhibitory effects.
  • Research is underway to test its anticancer effects and toxicity in humans
  • Maitake is thought to exert its effects through its ability to activate various effector cells, such as macrophages, natural killer cells, and T cells, as well as interleukin-1 and superoxide anions.
  • Maitake extract enhanced the growth and differentiation of mouse bone marrow cells treated with doxorubicin, a chemotherapeutic agent.
  • In addition, maitake extract may modulate antigen presentation as evidenced by protection of mice against tumor implantation following transfer of dendritic cells from tumor-bearing mice that were treated with maitake extract.
• Info from PubMed
  • Can maitake MD-fraction aid cancer patients? By Kodama N, Komuta K, Nanba H.Department of Microbial Chemistry, Kobe Pharmaceutical University, Kobe, Japan. Altern Med Rev. 2002 Dec;7(6):451; author reply 452-4.
  • Maitake mushroom (Grifola frondosa) MD-fraction containing beta-1,6 glucan with beta-1,3 branched chains has previously exhibited strong anticancer activity by increasing immune-competent cell activity.1,2 In this non-random case series, a combination of MD-fraction and whole maitake powder was investigated to determine its effectiveness for 22- to 57-year-old cancer patients in stages II-IV. Cancer regression or significant symptom improvement was observed in 58.3 percent of liver cancer patients, 68.8 percent of breast cancer patients, and 62.5 percent of lung cancer patients. The trial found a less than 10-20 percent improvement for leukemia, stomach cancer, and brain cancer patients. Furthermore, when maitake was taken in addition to chemotherapy, immune-competent cell activities were enhanced 1.2-1.4 times, compared with chemotherapy alone. Animal studies have supported the use of maitake MD-fraction for cancer.
  •  A 2001 study conducted at the Toya Medical and Pharmaceutical University in Japan found that Maitake  polysaccharides drastically increased the killing power of macrophage immune cells.
  • A recent study by researchers at the New York Medical College, found that polysaccharides from Maitake  drastically slowed the growth of prostate tumor cells.
• Wikipedia Researchers have also indicated that whole maitake has the ability to regulate blood pressure, glucose, insulin, and both serum and liver lipids, such as cholesterol, triglycerides, and phospholipids, and may also be useful for weight loss.
  • Maitake is rich in minerals (such as potassium, calcium, and magnesium), various vitamins (B2, D2 and Niacin), fibers and amino acids. One active constituent in Maitake for enhancing the immune activity was identified in the late 1980s as a protein-bound beta-glucan compound.
  • This year, a phase I/II human trial, conducted by Memorial Sloan–Kettering Cancer Center, showed Maitake could stimulate the immune systems of breast cancer patients. Small experiments with human cancer patients, have shown Maitake can stimulate immune system cells, like NK cells. In vitro research has also shown Maitake can stimulate immune system cells. An in vivo experiment showed that Maitake could stimulate both the innate immune system and adaptive immune system.
  • In vitro research has shown Maitake can induce apoptosis in cancer cell lines (human prostatic cancer cells, Hep 3B cells, SGC-7901 cells, murine skin carcinoma cells) as well as inhibit the growth of various types of cancer cells (canine cancer cells, bladder cancer cells).
  • Small studies with human cancer patients, revealed a portion of the Maitake mushroom, known as the "Maitake D-fraction", possess anti-cancer activity.
  • In vitro research demonstrated the mushroom has potential anti-metastatic properties.
  • In 1997, the U.S. Food and Drug Administration (FDA) approved an Investigational New Drug Application for a portion of the mushroom.
  • Research has shown Maitake has a hypoglycemic effect, and may be beneficial for the management of diabetes. The reason Maitake lowers blood sugar is due to the fact the mushroom naturally contains a alpha glucosidase inhibitor.

Agaricus blazei mycelia

• Agarius, one of the most powerful stimulants yet to be discovered, is a medicinal mushroom from Brazil that contains a rich complex of betaglukins, a type of polysaccharide which stimulates both humoral B-cells and cell media T-cells immunity.
•  University studies in Japan identify betaglukin polysaccharides that raised levels of immune cells. Populations of pan T-cells jumped 43%, helper T-cells 37% and killer T-cells 50% following oral administration of this polysaccharide.
• Info from Wikipedia
  • Due to the fact Agaricus blazei contains a high level of beta glucans, compounds known for stimulating the immune system, Agaricus blazei is used in oncological therapy in Japan and Brazil. In addition to beta-glucans, Agaricus blazei's effect on the immune system is believed to be due to other polysaccharides such as alpha-glucans.
  • In Japan, Agaricus blazei is also the most popular complementary and alternative medicine used by cancer patients.
  • Many researchers have studied Agaricus blazei, as well as other medicinal mushrooms for close to 50 years, due to laboratory tests which show they can stimulate immune system cells and immune system cytokines. A substance that could stimulate the immune system could have major implications for human health, and this is why mushrooms have gained attention from the international research community. Below is a summary of this research, which is often based on animal or cellular models. Research conducted on the mushroom's ability to impact the human immune system or human diseases is limited.
  • Research into potential cancer protective properties

(Results primarily from cell and animal model experiments)

Experimental Model Experimental Effect (in vitro) Experimental Effect (in vivo, mouse models)

Fibrosarcoma Inhibited growth via apoptosis induction (MethA tumor cells)[33] Inhibited growth[33]

Hepatocarcinoma Inhibited abnormal collagen formation (human hepatocarcinoma cells)[34][1]  

Leukaemia Induced apoptosis (human myeloid leukemia cells)[35] (U937 cells)[36] (HL-60 cells)[37] Inhibited growth[35][38]

Lung cancer Induced apoptosis (human LU99 cancer cells)[39] Inhibited metastasis, growth[40]

Melanoma   Inhibited growth[2]

Myeloma   Inhibited growth[41]

Ovarian cancer Inhibited growth and metastasis via apoptosis induction (human ovarian cancer HRA cells)[40] Inhibited metastasis, growth[40]

Prostate cancer Induced apoptosis (human PC3 cells)[42] Inhibited growth[42]

Sarcoma   Inhibited angiogenesis[43][12][27]

Skin cancer   Inhibited growth[3]

Stomach cancer Induced apoptosis (KATO III cells)[39]  

 

A human study of 100 gynecological cancer patients revealed Agaricus blazei consumption resulted in a significantly higher level of NK cell activity with a reduction in chemotherapy associated side effects.

 

Arabinogalactin (larch tree extract)

 

Larch Arabinogalactan is a Novel Immune Modulator  by Peter D'Adamo, NDOriginally published in: J. Naturopath. Med 1996 (4);32-39

 Dr. D'Adamo says "…Generally, larch arabinogalactan pretreatment induced an increased release of interferon gamma (IFN gamma), tumor necrosis factor alpha, interleukin-1 beta (IL-1 beta) and IL-6 but only IFN gamma was involved in enhancement of NK cytotoxicity (1).  He further states that arabinogalactan inhibits metastatic cell formation.  Please read his study at the following website:  http://www.dadamo.com/science_larch.htm 

 

The following are also found in ImmuPro and were discussed in the excerpt. 

 

limonene (from orange essential oil)melatonin (4mg =  dreamy sleep)calcium zinc selenium copper

As you will probably agree, ImmuPro is a cancer fighter.

 

 

****** SPECIAL THANKS TO  Connie Bynum, LMT FOR COMPILING THIS INFO